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| 伊维菌素与丙硫咪唑对内蒙古两地区放牧绵羊胃肠道线虫驱杀效果 |
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王鹏龙1, 罗晓平1,2, 敖登高娃1, 刘阳1, 方变变1, 李超3, 王瑞1, 李军燕2, 杨晓野1
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| (1.内蒙古农业大学 兽医学院, 呼和浩特 010018;2.内蒙古自治区农牧业科学院 兽医研究所, 呼和浩特 010031;3.内蒙古自治区兽药监察所, 010010) |
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| 摘要: |
| 为了解内蒙古地区放牧绵羊胃肠道线虫对常用驱虫药物的耐药情况，选取呼和浩特和林格尔地区和包头萨拉齐地区自然状态下，感染胃肠道线虫的放牧绵羊各60只，随机分为3组，每组20只，其中2个试验组分别采用伊维菌素或丙硫咪唑进行驱虫，对照组则不做处理，采用粪便虫卵减少试验方法，对其驱虫效果进行评估。结果表明：和林格尔地区绵羊胃肠道线虫使用伊维菌素或丙硫咪唑处理72 h后，粪便虫卵减少率分别是28%和77%；萨拉齐地区绵羊粪便虫卵减少率分别是40%和100%。研究发现：两地区放牧绵羊胃肠道线虫对伊维菌素有着较高的耐药性；和林格尔地区绵羊对丙硫咪唑耐药性程度较轻；在萨拉齐地区，丙硫咪唑驱虫效果较好。 |
| 关键词: 绵羊 内蒙古 伊维菌素 丙硫咪唑 胃肠道线虫 耐药性 |
| DOI：10.11841/j.issn.1007-4333.2019.11.13 |
| 投稿时间：2019-04-11 |
| 基金项目:国家自然科学基金项目（31660710）；内蒙古农牧业创新基金项目（CXJJM01） |
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| Effects of ivermectin and albendazole on the gastrointestinal nematodes of grazing sheep in Inner Mongolia |
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WANG Penglong1, LUO Xiaoping1,2, Aodenggaowa1, LIU Yang1, FANG Bianbian1, LI Chao3, WANG Rui1, LI Junyan2, YANG Xiaoye1
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| (1.College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China;2.Animal Husbandry Institute, Inner Mongolia Academy of Agricultural&Animal Husbandry Sciences, Hohhot 010031, China;3.Veterinary Drug Control Institute of Inner Mongolia Autonomous Region, Hohhot 010010, China) |
| Abstract: |
| To understand the situation of the resistance in gastroinstestinal nematodes of grazing sheep to current anthelmintics (ivermectin and albendazole),an investigation was carried out by taking 60 grazing sheep infected with gastroinstestinal nematodes in Helinger,Hohhot and Salaqi,Baotou as study objects.The grazing sheep were randomly divided into 3 groups with 20 in each group.Two experimental groups were respectively treated with ivermectin or albendazole,while the control group received no treatment.Faecal egg count reduction tests were employed to determine the efficacy of the these two drugs against gastroinstestinal nematodes infection.The results showed that the reduction in arithmetic mean faecal egg counts achieved by ivermectin or albendazole in Helinger were 28% and 77% after 72 h of treatment,respectively,and their effects were respectively 40% and 100% in Salaqi.This study indicated that there was high resistace of ivermectin against the gastrointestinal nematodes in grazing sheep in two areas and there were mildly resistance of albendazole in Helinger.However,albendazole appeared to be very effective on sheep in Salaqi. |
| Key words: sheep Inner Mongolia ivermectin albendazole gastrointestinal nematodes drug resistance |
