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| 生理电场对早期胚胎发育的影响 |
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王晓燕1,2, 王渝1, 赵三军1, 蒋文弢3, 蒋锐达1, 施利民1, 赵敏1,4
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| (1.云南师范大学 生命科学学院, 昆明 650500;2.云南师范大学 云南省生物质能与环境生物技术重点实验室, 昆明 650500;3.西弗吉尼亚大学 动物及营养科学部, 摩根敦 WV26506, USA;4.美国加州大学 戴维斯分校医学院, 加州 95616, USA) |
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| 摘要: |
| 胚胎发育涉及一系列复杂的生理学、细胞生物学以及基因组学过程。已有研究表明，胚胎发育早期特别是原肠胚和神经胚时期存在着一定强度的内源生理电场，当存在类似内源生理电场强度的外源电场时，能引导细胞迁移、控制细胞极化、调节细胞增殖和分化，从而在一定程度上影响胚胎发育。本研究主要就内源生理及外源电场对胚胎发育的引导或干扰作用进行综述，以期为胚胎发育研究提供新思路。 |
| 关键词: 胚胎发育 生理电场 外源电场 |
| DOI：10.11841/j.issn.1007-4333.2016.11.10 |
| 投稿时间：2016-01-16 |
| 基金项目:国家重点基础研究发展973计划（2012CB5l8100）；云南省高端科技人才引进项目（2009CI127） |
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| The effect of physiological electrical field on early embryo development |
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WANG Xiao-yan1,2, WANG Yu1, ZHAO San-jun1, JIANG Wen-tao3, JIANG Rui-da1, SHI Li-min1, ZHAO Min1,4
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| (1.School of Life Sciences, Yunnan Normal University, Kunming 650500, China;2.Key Laboratory of Biomass Energy and Environmental Biotechnology of Yunnan Province, Yunnan Normal University, Kunming 650500, China;3.Division of Animal and Nutritional Sciences, West Virginia University, Morgantown WV 26506, USA;4.School of Medicine, University of California, Davis, California 95616, USA) |
| Abstract: |
| Embryo development is a complicated process,which involves diverse physiological,cell biological and genomic processes.Current studies have shown that there is certain strength of endogenous electric field existing in early embryo development,especially in gastrula and neurula period.Similar strength of applied electric fields directs cell migration,polarization,proliferation and differentiation,which affect the early embryo development.The guidance and interference effects on embryo development by endogenous or applied electric fields are reviewed in this paper,which may provide a novel perspective on future researches on embryo development. |
| Key words: embryo development electric field extracellular electrical field |
