| 摘要: |
| 布鲁氏菌病是一种重要的人畜共患病, 也是引起动物繁殖障碍的主要疾病之一。近年来, 我国人、畜间布鲁氏菌病呈高发态势, 严重威胁畜牧业发展和人群身体健康。及时准确诊断对控制和净化布鲁氏菌病具有重要意义。本研究从病原学和血清学两方面对布鲁氏菌病的现有诊断技术进行概述, 同时指出布鲁氏菌免疫原性蛋白抗原的筛选和研究, 对布病的控制和净化意义重大。 |
| 关键词: 布鲁氏菌病 诊断 细菌学 血清学 分子生物学 |
| DOI：10.11841/j.issn.1007-4333.2014.06.23 |
| 投稿时间：2014-02-20 |
| 基金项目:北京农学院"大北农青年教师科研基金"(13ZK005);国家"973"计划项目(2010CB530202) |
|
| Research progress of brucellosis diagnostic techniques and immunogenic proteins |
|
WANG Zhen1, LU Lin1, WU Qing-min2
|
| (1.Animal Science and Technology College, Beijing University of Agriculture, Beijing 102206, China;2.College of Veterinary Medicine, China Agricultural University, Beijing 100193, China) |
| Abstract: |
| Brucellosis is an important zoonosis and one of significant causes of reproductive losses in animals.Recently, human and animal brucellosis has showed a high incidence trend in our country which seriously threatened the development of animal husbandry and the human health.Prompt and accurate diagnosis for brucellosis plays a key role in disease control and eradication.This review described the antigenic and serological methods used for the diagnosis of human and animal brucellosis.And also this review indicated that the screening and study of Brucella immunogenic protein antigens will be of great significance to the control and purification of brucellosis. |
| Key words: brucellosis diagnosis bacteriology serology molecular methods |
