| 摘要: |
| 兔2细胞期或8～16细胞期胚胎培养液立即或经冷冻、鲜冻后注入去脾小鼠体内,能异源性引起去脾小鼠血小板数量显著减少(P<0.050)。血小板激活因子受体竞争性拮抗剂海风藤酮能抑制这种作用。试验说明兔胚胎释放血小板激活因子,并引起去脾小鼠血小板的聚集。 |
| 关键词: 兔胚胎 去脾小鼠 血小板激活因子 海风藤酮 |
| DOI： |
| 投稿时间：1995-02-24 |
| 基金项目:本研究为国家自然科学基金 |
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| Effect of Rabbit Embryo Releasing Substance on Platelet Count of Splenectomized Mice |
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| Abstract: |
| Splenectomized mice were injected fresh or frozen-thawed 2-cell or 8-16-cell rabbit embryo- cultured medium.Rabbit embryo-cultured medium could cause a significant decrease(P<0.050)in platelet number of heterogeneous of splenectomized mice.Kadsurenone which is a competitive antagonist of platelet activating factor(PAF)receptor could inhibit this effect.Experiments illustrated that rabbit embryos released PAF and induced platelet aggregation of splenectomized mice. |
| Key words: rabbit embryo splenectomized mouse platelet activating factor(PAF) kadsurenone |
